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Science - Biology - Genetics

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MendelBase
- Proteomic database of functional and structural attributes. Includes examples of indexed proteins. Requires registration.
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Comparative and Functional Genomics
- Guidance from the U.S. Department of Energy and National Institutes of Health Guidance. Features abstracts, newsletter articles, and related resources.
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Center for Comparative Functional Genomics - University at Albany
- Promote interdisciplinary research in genomics, bioinformatics, proteomics, microarray, and confocal imaging. Includes facilities, staff details, employment, and graduate programs.
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UCSF Pharmacogenetics of Membrane Transporters Project
- Conduct research and a series of integrated studies to elucidate the pharmacogenetics of membrane transport proteins. Includes information on personnel, publications, training, and available data.
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Pharmacogenetics
- Publish research papers and articles on genetic determinants of response to drugs and other chemicals in humans and animals. Table of contents, author guidelines, editorial board and subscription information.
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Pharmacogenetics of Anticancer Agents Research Group - PAAR
- Identify and evaluate polymorphisms in drug metabolizing enzymes, transporters, or targets relevant to anticancer agents. Includes publications, training, and related links.
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Pharmocogenetics Knowledge Base
- Integrated resource about how variation in human genetics leads to variation in response to drugs.
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Center for Pharmacogenetics
- Research program bridging together pharmacy and genetics. Features mission overview, research programs, and faculty members .
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Pharmacogenomics: The Promise of Personalized Medicine
- Review paper which discusses a range of issues including an historical perspective and potential future trends.
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American Medical Association
- Provides examples, scenarios, implications, definitions, and the economics of pharmacogenetics.
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National Institute of General Medical Sciences
- Provides information on the institute's pharmacogenetics research network . Includes links to program announcements, news and events, and resources.
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GCRC Pharmacogenetics Core Laboratory
- Facilitate mechanisms for evaluation of pharmacogenomic endpoint measurements. Features an overview of services, available tests, personnel, and related links. University of Pittsburgh.
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Pharmacogenomics: Medicine and the New Genetics
- Overview, anticipated benefits, and links to related resources. From the U.S. Human Genome Project.
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Mirage
- Information methodologies, tools, and technologies relating to the study of gene expression and signal transduction from the Institute for Transcriptional Informatics.
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GeneExpress
- Designed for analysis of genomic regulatory sequences of higher eukaryotes. Includes several databases and programs for visualization of the information contained .
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GEML Community
- Markup language used as a standard method of exchanging gene expression data along with the associated gene and experiment annotation. Includes document type definition and tagging references.
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SAGEmap
- An experimental technique designed to gain a quantitative measure of gene expression. Provides information and downloads on mappings and tools, and related resources.
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Exploring the Metabolic and Generic Control of Gene Expression
- Contains the complete data sets for the experiments in the paper - DeRisi et. al. Science 278: 680-686, as well as the images of the whole-genome microarrays. Includes text files that can be downloaded.
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Genome-Wide Expression
- The Young Lab at the Whitehead Institute for Biomedical Research. Use genome-wide expression analysis to dissect the transcriptional regulatory circuitry of the cell.
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Prokaryotic Genetics and Gene Expression
- Features regulation of Prokaryotic genes. Includes study tools, the Lac Operon, and practice problems. From the Massachusetts Institute of Technology.
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Stanford Microarray Database
- Stores raw and normalized data from microarray experiments, and corresponding image files. Some data access is limited to registered Stanford researchers. Makes available online analysis tools. Code base is open source and available for download.
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Stanford Genomic Resources
- Provides links to various systematic analysis projects, resources, laboratories, and departments at Stanford University. Includes databases, and genome centers and projects.
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Genex
- Project to provide an online repository of gene expression data with an integrated toolset . Includes programs and software. From the National Center for Genome Resources.
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Molecular Cytogenetics and Genome Evolution
- Study of the function of the cell nucleus, and the nature, evolution, expression, recombination and segregation of the DNA sequences within the nucleus at interphase.
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The Germplasm Resources Information Network
- Provides germplasm information and links about plants, animals, microbes and invertebrates within the National Genetic Resources Program (NGRP) of the USDA-ARS.
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Aldehyde Dehydrogenase Gene Superfamily Database
- Features a range of databases which consist of homologous gene families, which are clusters of genes from different genomes that include both orthologs and paralogs.
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Boeke Laboratory
- Study the molecular mechanism of transposition in eukaryotes. Includes staff profiles, publications, research tools, and course information.
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PLACE
- Database of motifs found in plant cis-acting regulatory DNA elements in vascular plants and their variations in other genes or in other plant species are also compiled.
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Mendel Plant Gene Nomenclature Database
- Develop a common nomenclature for sequenced plant genes. Database lists a range of topics including gene families, products, synonyms, and names, allelic designations and genomes.
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Plant Genome Data and Information Center
- Provides access to a variety of information, products and services on a range of plant and animal genome mapping. From the National Agricultural Library of the US Department of Agriculture.
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International Plant Genetic Resources Institute
- Seeks to advance the conservation and use of genetic diversity. Site includes maintenance and conservation of genetic resources of crops, forestry and related species, regional programs, networks, links, and information on events and training programs.
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Plant Gene Register
- An electronic publication for articles describing the isolation and DNA sequence determination of plant genes.
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Computational Biology Centers
- Provides information on research projects, including the EST projects and management, and software development.
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USDA-ARS Center for Bioinformatics and Comparative Genomics
- Links to multiple plant and model genome databases. From Cornell University.
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Plant Patent
- Provide information about protecting new variety and trademarks. Information is also available about license agreements and how to enforce patents and trademark rights.
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Plant Molecular Biology Center
- Promotes, coordinates, and facilitates research activities in plant molecular and cellular biology. Includes information on the Core DNA sequencing facility. From Northern Illinois University .
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Nordic Gene Bank
- A plant genetic resources centre for Nordic agriculture and horticulture. Includes a database for searching for cultivars or accessions stored for specific taxa and a library containing information on the institutes publications.
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Plant Genome Data and Information Center
- Resource site, from the National Agricultural Library of the US Department of Agriculture . Includes publications and related links.
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The System-Wide Information Network for Genetic Resources - SINGER
- International Agricultural Research Centres of the Consultative Group on International Agricultural Research . Provides access to information on the collections of genetic resources held by the CGIAR centres.
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C-Fern - A Plant For Teaching and Research
- Educational materials for teaching plant biology using hands-on and inquiry-based investigations and independent student-initiated research. Uses the tropical homosporous fern genus Ceratopteris as a model plant system.
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Genoplante
- Joint programme in plant genomics, in which public institutes and private firms are implicated. Provides an informative and educational resource on crop improvement and genomic studies.
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The UK Crop BioInformatics Network
- Individual databases for Arabidopsis, Barley, Brassica, Forage grasses, Millet and comparative analysis . Also develops new tools and displays to highlight the agronomic significance of comparative analysis.
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Institute for Plant Genomics and Biotechnology
- Develop plant biotechnology, genomics, and related life science technologies for crop improvement . Includes research data, development laboratories, and staff profiles.
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Plant Genomics at Cirad
- Aimed at assisting breeding programs. Features molecular analysis of genetic diversity, genome mapping, somatic embryogenesis, and genetic transformation.
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Lam Laboratory
- Project to chart the relative physical position and movement of sequences for each of the chromosomes in cells of living plants. Includes project plan, 3d map, technology, and references.
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Photosynthetic Mutant Library
- Library of transposon induced maize mutants, DNA samples, and phenotypic data, available for the study of chloroplast biogenesis. Includes user guidelines, protocols, and controls.
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Institute of Plant Breeding ( IPB )
- Established under the College of Agriculture at the University of the Philippines Los Banos (CA-UPLB), Laguna. It is the national breeding center for all crops, except rice.
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Chlamydomonas Chloroplast Genome
- Interactive website for information pertaining to the now sequenced Chloroplast genome of Chlamydomonas reinhardti. Includes genetic center, genome project, database, maps, and sequencing tools. Cornell University.
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Donach Plant Breeding Academy
- Education, comment and research in plant breeding based on natural genetics, including quantitative population genetics.
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Plant Breeding - North Carolina State University
- Offers a range of information on research programs, courses, and crops. Includes facilities, history, meetings, and photographs.
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DNA LandMarks, Inc.
- Develop molecular plant breeding tools.Research includes molecular mapping, map-based cloning, and DNA markers.
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Plant Molecular Biology Lab at Penn State
- Basic and applied research in plant biotechnology and molecular biology by Mark Guiltinan.
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Centre for Genetic Resources, The Netherlands (CGN)
- Provides information on research and protocols and crop collections including European and international reference collections of Brassica and Lettuce. Includes a searchable database.
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Plant Gene Expression Center
- Conducts fundamental research in plant molecular biology. Includes an overview of research, facilities, seminars, links, and directions.
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Plant Genome Mapping Laboratory at the University of Georgia
- Identify and implement DNA diagnostic tools that are predictive of specific plant characteristics, and identify genes that are responsible for plant development, evolution, or agriculture.
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Rice Genome Research Program
- Aims to completely sequence the genome and to pursue goals in functional genomics, genome informatics and applied genomics. Features a database integrating the genetic map, physical map and sequencing information .
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Maize Genome Database
- Source for information on genetics and molecular biology. Features a searchable index of current knowledge about the genome and its expression.
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Cytoplasm Genome Research
- Abstract molecular analysis, cytoplasm types, general breeding strategies and a listing of publications.
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Genome Database Resource
- Offers web interfaces to GrainGenes and Soybase, FTP archives for a collection of plant genome databases, and links to other servers for plant databases and crop newsletters.
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The Greek Vitis Database
- A multimedia web-backed genetic database for grapevine in Greece. Offers a cluster of 6 databases compiling information, genetic identity profiles obtained with specific nuclear and chloroplast markers, image documentation and phenograms.
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Weeds World
- Archives of international electronic newsletter on Arabidopsis research. This newsletter is no longer actively curated.
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Arabidopsis cDNA Sequence Analysis Project
- Provides a system that facilitates the analysis of cDNAs, or expressed sequence tags for determining putative function and other studies.
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ABRC cDNA Clones
- Provides access to information on EST clones available from the Arabidopsis Biological Resource Center .
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Arabinet
- Links to arabidopsis online information, including informatica and stock centres, genetic maps and physical map graphics .
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Bionet.Genome Arabidopsis Newsgroup Archive
- Electronic communication forums used by biological scientists worldwide. No fees are charged for the service.
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Cold Spring Harbor Laboratory
- Global consortium of researchers involved in the comprehensive Arabidopsis Genome Sequencing Project, mapping and sequencing the entire genome of a flowering plant.
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Lehle Seeds
- Supplier of arabidopsis seeds, products, literature and services. Features a range of resources and links, including publications, news groups, software, and teaching.
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Arabidopsis Information Resource (TAIR)
- Comprehensive information resources for the scientific community working with this model plant. Includes a searchable relational database with a range of datatypes.
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The Nottingham Arabidopsis Stock Centre
- Provides seed and information resources to the International Arabidopsis Genome Programme and the wider research community. Includes catalog, staff profiles, protocols, and links
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Genomic Arabidopsis Resource Network
- Provides Arabidopsis researchers with tools of functional genomics: microarrays, proteomics, metabolomics and tagged mutant populations.
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Chentao Lin Laboratory
- Studies the regulation of arabidopsis development by photoreceptors, with an emphasis of the blue light receptor cryptochrome 2 . Features staff profiles, publications, and journals.
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Arabidopsis Genome Resource
- Information resource at NASC which aims to integrate sequence data with physical and genetic maps of arabidopsis and provide information for identifying gene function and crop plant orthologues of arabidopsis genes.
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Arabidopsis Seed EST Project
- Provides a new set of expressed sequence tags from developing seeds. Includes an online database, and downloadable data and sequence documents.
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Deng Lab at Yale University
- Studies the light control mechanisms involved in arabidopsis seedling development. Includes abstracts of papers, table of cop/det/fus mutants, and related sites.
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Arabidopsis Thaliana Annotation
- Database of annotated coding sequences from genomic DNA sequencing. Contains the completed version of Chromosome 2 sequence and annotation.
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The Genetics and Molecular Biology of Ovule Development
- A molecular and genetic analysis of plant organogenesis using the ovules of arabidopsis as the model system. Includes early and current research, and a bibliography.
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Genoscope
- Determine the end sequences of the BAC clones from both TAMU and IGF libraries. Includes results, preparation protocols, and sequence and chromatogram visualisation.
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MIPS Arabidopsis Thaliana Group
- Features a database of sequences for chromosomes and organelles available in both graphical and text view. Includes a guided tour.
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The TIGR Arabidopsis Thaliana Database
- Provides a collection of information on genome research, including chromosomes, RNA gene table, gene survey charts, and sequence data.
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Salk Institute Genomic Analysis Laboratory
- Global expression studies. Features genomic annotation, full-length cDNA sequence and insertion mutant databases.
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Arabidopsis Thaliana Genome Sequencing Center
- Provides access to preliminary and finished sequences via the ftp site or blast server. Project at Washington University.
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Genomics of Loblolly Pine
- Project to identify and characterize genes that are important in wood formation and their affect on the properties of wood and its derived products. Includes a gene database, library, and clone information.
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Dorena Tree Improvement Center
- Provides forest genetic services to the national forests and cooperators in Oregon and Washington. Includes an overview of services, center history, current programs and photographs.
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Dendrome
- A collection of forest tree genome databases and other genetic information resources for the international forest genetics community.
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The Institute of Forest Genetics
- Features information on research areas and programs, facilities and staff, publications, and resources.
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Forest Genetics and Tree Breeding
- Offers a collection of links to a range of subjects including conservation of forest genetic resources, dendrology, and journals and books.
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Bean Genes
- Genome databases for a number of crop species. Includes molecular mapping data, germplasm information, trait studies, identified quantitative trait loci, and pathogen descriptions.
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Laboratory of Experimental Modelling of Evolutionary Processes
- Use the garden pea as a genetic model to construct genetic systems which would produce variation in the dose of histone H1 genes. Includes a Pisum sativum genetic map. Novosibirsk Institute of Cytology and Genetics.
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Pea EST Database
- Includes cDNA sequences from different tissues (seed, flower, leaf, and root) of garden pea (Pisum sativum) and their homology description of Blast searches.
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Bean Evolution and Genetics
- Features a range of information on Phaseolus and Vigna including research, publications, and genome mapping.
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SoyBase
- Genome database for Glycine. Searchable by category including map collections, genes, sequence, and trait.
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Designer Seeds
- Explores recent advances in the genetic engineering of plants, that have developed crops genetically endowed not only to resist damage from insects but also to be resistant to herbicides.
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Genetic Modification and Biosafety Assessment Research Group
- Collate documents, reports and informed comment relating to the scientific research application, regulation, socioeconomic and environmental implications of genetically modified crops.
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Transgenic Crops
- Features information about transgenic crops, also known as genetically modified organisms, GMOs, or GM crops. Includes links to other resources on the technology and issues surrounding transgenic crops .
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Genetically Modified Rice
- Offers a basic overview incorporating both potential benefits and risks as well as a basic description of the modification method used .
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Ohio State University's Plant Transformation Laboratory
- Studies and refines methods of crop plant transformation. Includes transgenic soybean and wheat, laboratory images, and related links.
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Animal Genetics and Breeding Unit - AGBU
- Carry out research, development and training in the genetic improvement of livestock for the benefit of Australian agriculture. Includes databases, publications, education, and employment.
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The Friends of BLUP
- An Italian discussion group on animal genetics. BLUP is the acronym of Best Linear Unbiased Prediction, a genetic evaluation method.
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Animal Breeding and Genetics Group, Wageningen University
- Aims are the identification of the role of genetic factors in the functioning of farm animals and the design of optimum schemes for long-term selection. Includes research, education, and publications.
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Avian Genetic Population Structure
- Studies in the advancement of population level genetic analyses in birds. Includes information on research and polymerase chain reaction based fingerprinting technology.
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Spermatology
- Links, images, and information, including report on "Sperm-mediated gene transfer: advances in sperm cell research and applications" . From Murdoch University, Australia.
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HOVERGEN
- Database of homologous vertebrate genes. Allows selection of sets of genes among species, and to visualize multiple alignments and phylogenetic trees.
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The Cancer Genome Anatomy Project
- Excellent tool for searching and analyzing known, tissue-specific, tumor genes - from the National Cancer Institute.
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Genetic Information Systems
- A project to design and built computer systems to support cancer genetic risk analysis and act as a resource site for healthcare workers in the field and the general public.
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Arizona Telemedicine Breast Cancer Protocols
- A list of breast cancer protocols currently underway at the Arizona Cancer Center.
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Imperial Cancer Research Fund's Molecular Pathology Laboratory
- Dedicated to researching the causes of and treatments for cancer. Includes description of the molecular genetics of pancreatic cancer, and related research into screening, diagnosis, treatment, and genetic vaccination.
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The Genetics of Cancer
- Provides general and detailed information for both patients and health professionals wanting to learn more about the genetics of cancer.
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Chimeric Therapies Inc
- Provides a listing of ongoing FDA-approved bone marrow transplant clinical trials for leukaemia patients, and links to participating centers and patient resources.
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CancerNet
- Informative site providing detailed information about genetics, causes, risk factors, and prevention of cancer. The information is aimed at both patients and health professionals.
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Breast Cancer Gene
- A name and fact interconnected searchable database. From the Baylor College of Medicine .
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Biotechnology and Cancer Research
- Educational links for professionals and researchers in the field of cancer genetics, including the method of fluorescence in-situ hybridization and its applications.
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Atlas Chromosome in Cancer
- Concise and updated reviews on genes, cytogenetic and clinical entities in cancer, and on cancer-prone diseases; it is also a portal towards databases devoted to genomics and cancer.
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Telomere Cancer Theory
- A paper on a genetic model for the cause of cancer describing a counter mechanism for the cell's life span and how this counter can cause cancer.
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Cancer Risk Analysis
- Includes a listing of links to journals, articles and related resources on the computational methods of evaluating breast cancer risk based upon family and genetic history.
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American University of Beirut Medical Center
- Maintain a tumor registry and administer and keep records of regular interdisciplinary tumor conferences . Offers guiddes and protocols, photographs and history of the center.
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Cancer Genetics and Developmental Biology
- Research focuses on identifying genomic changes, and signaling and metabolic pathways associated with tumour progression. Includes information on research groups, staff, and related resources.
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M. D. Anderson Cancer Center - Molecular Genetics
- Department uses molecular genetic approaches to study cell and tissue differentiation, and the genetic basis of human disease, including cancer. provides information on the faculty, graduate education, and seminars.
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Cancer Genome Anotomy Project - CGAP
- Determine the gene expression profiles of normal, precancer, and cancer cells. Includes human and mouse genome data, information on methods and resources for reagents, and informatics tools.
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The Jackson Laboratory
- Perform basic research on the genetic factors underlying cancer. Includes research data, education, courses and conferences, and career opportunities.
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Special Project Angiogenesis
- Offers a look at angiostatic therapy, cancer, genes, publications, and lab news. Includes goals, tools, and participants at the First Interdisciplinary Scientific Project on Tumor Angiogenesis sponsored by Italian Association for Cancer Research.
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ChickGBASE
- The Genome database of the chicken at the Roslin Institute (Edinburgh).
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Chicken Genome Project
- Information, newsletters, databases, and internet links related to poultry genome mapping. Michigan State University.
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Chicken Genome Mapping at Roslin Institute
- Aims to construct an integrated genetic and physical map of the chicken genome, to provide a public genome database and to co-ordinate genome mapping activities in poultry.
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Caenorhabditis Elegans WWW Server
- Offers genome data, features an introduction to the field, a list of worm labs, literature, meeting announcements and software.
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Caenorhabditis Genetics Center
- Coordinate and maintain a range of data. Includes databases and maps, bibliography, nomenclature, and a strain list.
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Caenorhabditis Elegans Network
- Provides navigation to information and data on a range of topics including genetics, bioinformatics, aging, and oxidative stress.
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Vanfleteren Lab
- Research at Ghent University, Belgium, including ageing , molecular phylogeny of nematodes, and Globins: structure-function relationships.
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Blaxter Lab Nematode Genomics
- Features sequencing data, evolution and development, phylogenetics, and links to filarial data. Includes a genetics course, research techniques and references.
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Blaxter Lab Nematode Genomics
- Sequence expressed sequence tags from parasitic nematode species to identify new drug and vaccine targets. Includes an experimental cluster database searchable by both annotation and sequence homology.
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Wheaton Genomics Research Group
- A collection of search and visualization tools for regulatory sites in intergenic regions of the organism C.elegans, including a motif lexicon.
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Medakafish
- Offers a range of data on the genome, genomic libraries, strains, and breeding. Includes a linkage map and expression sequence tags.
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Tilapia Genome Project
- Constructs genetic maps to facilitate the improvement of strains. Includes links to mapping database and reference family DNAs.
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Tetraodon Nigroviridis Genome Analysis
- Sequencing project . Includes an introduction, genome characteristics, photograph album, and related resources.
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Rainmap Database
- Mapping the Salmonids ( Rainbow Trout ) genome . Includes gene, sequencing, and phenes data, submission details, and related links.
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Rainbow Trout Genetic Map Dataset
- Features data using doubled haploids produced by androgenesis from the hybrid between two clonal rainbow trout lines. Includes project background.
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Salmon Genome Project
- Focuses on genome organisation, gene functions and data interpretation. Contains genetic and physical maps, bac and est libraries, sequence database and data query system.
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Zebrafish Information Network
- Extensive information on Danio rerio, including genomics databases, developmental stages, publications and molecular tools.
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Zebrafish Information Server
- Provides information, news and updates of general interest to the research community . It is maintained by Richard Vogt from the Department of Biological Sciences at the University of South Carolina.
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Tübingen Map of the Zebrafish Genome
- Features radiation hybrid and genetic maps. Includes an introduction, project data, protocol and submission details, and raw data.
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The MPIMG Zebrafish Projects
- Projects include oligofingerprinting of cDNA libraries, a physical map of the zebrafish genome , whole mount in situ screen gene expression profiling and rapid genetic mapping techniques.
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WashU-Zebrafish Genome Resources Project
- Develop genomic and genetic tools to facilitate biological investigations . Projects include expressed sequence tags, mapping genes and ESTs, and allocating and designing EST mapping primers.
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Stanford Zebrafish Genome Project
- Comparisons of zebrafish and mammalian gene maps. Includes maps, tables, and figures of conserved chromosomal segments .
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Myers Lab
- Study the neurobiology of the zebrafish using several imaging techniques, such as timelapse video microscopy, epifluorescence and confocal microscopy, and various quantitative fluorescence methods.
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Mammalian Genetics and Genomics
- The generation, mapping, and functional analysis of mouse models for human genetic diseases. Includes research programs, news, and staff profiles. From the Oak Ridge National Laboratory .
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Center for Mammailian Genetics
- Conducts and facilities interdisciplinary studies related to the genetic basis of human diseases. Features research facilities and graduate studies. University of Florida .
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Veterinary Genetics Lab
- Resource DNA-based diagnostic techniques for domestic and wildlife species and animal diseases .From the School of Veterinary Medicine,University of California .
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Institute of Experimental Genetics
- Focus on the functional analysis of the mammalian genome. Features research areas and groups, staff members, and related links.
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NIH Rat Genomics and Genetics
- Serves as a central point for information on NIH sponsored and related rat genetic and genomic activities and resources. Includes courses and meetings, reports and publications, and related resources.
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Genetic Maps of the Rat Genome
- Images of genetic linkage maps resulting from the integration of two F2 intercrosses (SHRSP x BN and FHH x ACI).
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Rat Genome Database - RGD
- Collaborative effort between research institutions involved in genetic and genomic research. Features genes, SSLPs, ESTs, QTLs, strain information and a range of tools.
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Rat Mapping Resources
- Links to genetic and radiation hybrid maps, markers and other resources from The Wellcome Trust Centre for Human Genetics.
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Rat-Est Project - University of Iowa
- Features RH maps and clone information cross-referenced to cluster information. Includes sequence analysis procedures and lab protocols .
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RATMAP
- Database covering genes physically mapped to chromosomes in the laboratory rat. Literature references to each mapped gene are also given and support for comparative mapping to several species.
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Rat Genome Data
- Details genetic markers, polymorphisms and maps, links to related data available in the mouse genome database, and other resources.
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Mouse Atlas and Gene Expression
- Project to develop a 3-D computer model of successive stages of mouse embryonic development for use in mapping the expression of different genes. Features a number of databases and interactive images.
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Mouse Genome Informatics
- Contains information on genetic markers, molecular segments, phenotypes, comparative and experimental mapping data. Includes graphical displays for genetic, physical, and cytogenetic maps.
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NIA/NIH Mouse Genomics
- Features searchable databases for t-complex genome sequencing and cDNA clone set. Includes staff profiles and postions available.
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InGenious Targeting Laboratories
- Provide mouse gene knockout and DNA sequencing services to academic and commercial researchers. Includes an overview of services and a listing of clients.
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Ozgene
- Commercial venture established to produce genetically modified mice. Includes an overview of services, research and development, and publications, .
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Mutagenicity: The Mouse Lymphoma Assay
- Discussion to understand mutations occurrence and production. Author suggests how mutations relate to human health and discusses detection of agents that induce such mutations.
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Mymouse.org
- A scientific collaboration for mouse mutant research. Includes a database of mutant mice available for phenotypic screening, and a listing of laboratories.
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Mouse Genome Centre - Harwell
- Undertake a range of research including molecular genetics, genomics, mutagenesis, transgenesis and informatics. Includes mapping research and projects, and sequencing program.
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Mutant Mouse Database
- Collection of several hundred mouse stocks, most of which propagate mutations induced by radiations or chemicals in various stages of male or female gametogenesis. From Oak Ridge National Labs.
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Upenn Transgenic and Chimeric Mouse Facility
- Provides a centralized service to efficiently produce transgenic mice for basic research. At the University of Pennyslyvania.
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Yale Transgenic Mouse and Gene Targeting Resource
- Produces transgenic and knock out mice for cancer center members and members of the Yale community.
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University of Michigan Transgenic Animal Model Core
- The Transgenic Core routinely prepares transgenic mice and mice with targeted mutations for University of Michigan investigators.
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Transgenic Animal Service of Queensland
- Service run by the University of Queensland's Institute for Molecular Biosciences which provides transgenic mice and other related services for Australian Science.
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University of Hawaii
- News release that was reported in the journal nature concerning the first reproducible cloning of mammals from adult cells.
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UC-Davis Transgenic Mouse Research
- Transgenic histopathology laboratory at the University of California-Davis providing comprehensive light and electron microscopic analysis of tissues submitted by interested investigators .
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TBASE
- A free, public domain database of targeted mutants and transgenic animals, specifically mice, generated and analyzed worldwide.
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European Mouse Mutant Archive (EMMA)
- A non-profit repository for the collection, archiving and distribution of relevant mutant strains essential for basic biomedical research.
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Mouse Knockout & Mutation Database (MKMD)
- A fully searchable database of phenotypic information related to knockouts and classical mutations in mice. Requires subscription.
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ORNL Mutant Mouse Database
- Oak Ridge National Laboratory's Mutant Mouse Database
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Cre Transgenic Mice Database
- An updated list of all available Cre transgenic mice alongwith contact addresses.
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Bay Area Resource of Mouse Mutations
- Resource of insertional mutations in mouse embryonic stem cells, especially mutations in secreted and membrane proteins.
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The Big Blue Website
- Contains literature and data on mouse models transgenic for retrievable mutation shuttle vectors. Particulary useful for mutation analysis in mammalian system.
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McLaughlin Research Institute
- Not-for-profit mouse mutagenesis program.
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Riken Large Scale Mutagenesis Program
- A large scale mouse ENU mutagenesis project at Riken GSC, Japan.
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GSF ENU-Mouse Mutagenesis Screen
- ENU-Mouse Mutagenesis Screen in the German Human Genome Project
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Harwell Mutagenesis Programme
- A large scale mouse genetics programme to identify new phenotypes of relevance to human disease through ENU mutagenesis.
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BCM Mouse Genome Project
- Large scale ENU based mouse mutagenesis for developmental defects
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Trans-NIH Mouse Initiative
- A central information resource on NIH's trans-NIH mouse initiative.
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CMHD ENU Mutagenesis
- Centre for Modeling Human Disease (CMHD) use genome-wide ENU based random mutagenesis in mice to discover new genes and create new mouse models.
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German Gene Trap Consortium (GGTC)
- The German Genetrap Consortium (GGTC) generates a reference library of gene trap sequence tags (GTST) from insertional mutations generated in mouse embryonic stem (ES) cells.
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Tufts University School of Medicine, Transgenic Core Facility
- The Tufts-New England Medical Center and Tufts University School of Medicine Transgenic Core Facility (TCF) is a fee-for-service facility.
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Emory School of Medicine,Transgenic Mouse & Gene Targeting Core Facility
- The Transgenic Mouse and Gene Targeting Core Facility is a shared core resource of the Emory University School of Medicine and the Winship Cancer Institute.
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UMass Medical School:Transgenic Knockout Animal Core Facility
- The mission of the Transgenic-Knockout Animal Core Facility is to produce genetically-altered mice for the UMASS Medical School Community.
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CWRU School of Medicine:Transgenic Mouse Core Facility
- The CWRU School of Medicine Transgenic Mouse Core is a state-of-the-art pronuclear injection facility that was created to provide service to the CWRU research community.
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Transgenic Animal Web
- Links to useful transgenic resources
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Mount Sinai School of Medicine: Mouse Genetics Shared Research Facility
- The institutional Mouse Genetics Research Facility has been established to provide the Mount Sinai research community with access to state-of-the-art facilities for the production of transgenic and knockout mice.
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Herbert Irving Comprehensive Cancer Center :Transgenic Mouse Facility
- The Facility produces transgenic mice by microinjecting investigator-provided DNA into fertilized mouse eggs and chimeric mice by microinjecting embryonic stem (ES) cells into mouse blastocysts.
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Transgenic Models of Skin Disease Core
- Transgenic Models of Skin Disease Core at the Harvard Skin Disease Research Center
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KUMC :Transgenic and Gene-targeting Institutional Facility
- The Transgenic and Gene-targeting Institutional Facility (TGIF) at the University of Kansas Medical Center (KUMC) provides a centralized facility for production of transgenic mice.
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Medical College of Wisconsin : Transgenic Core Facility
- A Small Animal Transgenic Facility has been added to the Animal Resource Center providing Transgenic Services for the MCW research community.
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John Curtin School, ANU : Gene Targeting Laboratory Research,
- Gene targeting laboratory at The John Curtin School of medical research, Australian National University.
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BUMC: Transgenic Mice Core
- The mouse core facility at Boston University School of Medicine provides centralized, expert service to produce successfully transgenic as well as knock out mice for investigators at Boston University and as an outside service.
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Purdue University Transgenic Mouse Core Facility
- The Purdue University Cancer Center Transgenic Mouse Core Facility (TMCF) is located in the Hansen Life Sciences building and serves as a centralized resource for the production of transgenic and gene-targeted mice for Purdue investigators.
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SUNY-Stony Brook Transgenic Mouse Facility
- The Transgenic Facility is available for consultation and to conduct transgenic (pronuclear DNA injection) and gene-targeting projects in mice.
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UC-Irvine Transgenic Mouse Facility
- Home Page of the Transgenic Mouse Facility at UC-Irvine. The TMF is a core facility serving the UCI community, other UC campuses, and outside collaborators of UC researchers.
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UCSD Transgenic Mouse Core
- The Transgenic Mouse and Embryonic Stem Cell Gene Targeting Core is a state-of-the-art facility that has an outstanding track record in the production of genetically altered mice.
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MCDB Transgenic Facility
- MCDB Transgenic Facility,University of Colorado, Boulder, CO.
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UCHSC-Transgenic Mouse Core Laboratory
- University of Colorado Health Sciences Center. Transgenic Mouse Core Laboratory.
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UF Shands Cancer Center-Transgenic Mouse Core Facility
- University of Florida Shands Cancer Center. Transgenic Mouse Core Facility.
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UVA Transgenic Mouse Core Facility
- The Transgenic Mouse Core Facility of the University of Virginia (TMCF) provides centralized, expert service to efficiently produce transgenic and knockout mice for basic research for investigators at UVa.
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The Cancer Center at Washington University (St. Louis) - ES Core
- The Embryonic Stem Cell Core has been created to help create mutations in murine embryonic stem cells. The core has several missions, including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation.
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University of Kentucky Transgenic Facility
- The facility provides state-of-the-art equipment and expertise essential for producing transgenics and maintains a mouse colony.
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UM SCCC --Gene Knockout and Transgene Facility
- The University of Miami Transgenic and Targeted Mutant Mouse Core Facility is subsidized by the Sylvester Comprehensive Cancer Center. The primary objective of the facility is to efficiently produce transgenic mice and targeted-mutant mice
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University of Missouri-Columbia Transgenic Animal Core
- University of Missouri-Columbia Transgenic Animal Core
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UNC Lineberger: Animal Models Core Facility
- University of North Carolina at Chapel Hill. The Facility makes animal models of human disease for medical researchers by creating genetically modified mice. Transgenic and gene-targeted animals are generated from DNA constructs provided by clients.
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University of Texas Health Science Centre at Houston
- The Laboratory for Developmental Biology is a shared service support facility of the Institute in which embryonic stem cell lines, knock-out mice and transgenic mice are being produced.
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UTMB Transgenic Mouse Facility
- This state-of-the art facility, supported by the Sealy Center for Cancer Cell Biology, is available for use by all UTMB scientists.
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University of Texas M. D. Anderson Cancer Center Transgenic Core
- The Transgenic Animals Facility Core is located in the Griffin Animal Research Facility on the U.T.M.D. Anderson Cancer Center Science Park - Research Division campus.
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Wadsworth Center -Transgenics and Gene Knockout
- Transgenics and Gene Knockout - Wadsworth Center Core Facilities, New York State Department of Health.
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Vanderbilt-Ingram Cancer Center Transgenic Mouse / Embryonic Stem Cell Shared Resource
- Transgenic Mouse/ES Cell shared resource at The Vanderbilt-Ingram Cancer Center.
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UCLA Transgenic Mouse Facility
- The transgenic mouse facility will make transgenic mice for investigators at UCLA by microinjection of DNA into fertilized mouse eggs. It will also create gene knock out mice by injection of engineered ES cells into blastocysts.
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UCSF- Transgenic/Targeted Mutagenesis
- The primary purpose of the Transgenic/Targeted Mutagenesis Shared Resource facility is to provide microinjection services for investigators interested in generating mutant mice.
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Tennessee Mouse Genome Consortium
- The Consortium's purpose is to promote mouse models for human genetic diseases and as subjects for the study of gene function.
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Medical University of South Carolina - Alexander Awgulewitsch Transgenic Mouse Facility
- Core transgenic mouse research facility at the Medical University of South Carolina. Directly involved in skin and hair development research.
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AnTeq Transgenic Mice
- Generation of transgenic mice using oocyte microinjection and embryonic stem cell technology. Location: Switzerland
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DNX Transgenic Sciences
- Contract research organization specializing in the genetic modification of mice and rats using gene addition, gene targeting, homologous recombination, and microinjection techniques.
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InGeniousTargeting Labs
- iTL is a laboratory that specializes in providing mouse gene knockout and DNA sequencing services to academic and commercial researchers in various fields.
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Lexicon Genetics Inc
- Large scale production and sale of mouse ES cell clones. Each clone contains a gene trap event in a single gene that may be used to identify the function of a particular gene.
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Macrogen
- Offers customized transgenic mouse developing services to scientists in the field of biomedical research. Also develop cancer related DNA Chip using the cDNA microarray method. Location: South Korea
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Mice & More GmbH
- Offers an overview of services including conditional and consitutive knock-out and knock-in generation, animal model development, and phenotyping. Location: Germany
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Tosk, Inc.
- Offers a transgenic rodent production service. Includes an overview of services, advantages, and pricing.
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VisGenYx Animal Models
- Production of transgenic and gene targeted mice and customized research. Location: Estonia
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Regeneron Velocigene
- Velocigene -A novel high-throughput approach that is amenable to creating many preclinical disease models.
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Deltagen Target Discovery and Validation
- Large scale generation and characterization of mouse gene knockouts. The data are consolidated in Deltabase- Deltagens in vivo mammalian gene function database.
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Iffa Credo - Transgenic Services
- A Charles River company, offers custom transgenic and gene targeting services.
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BK Universal Ltd
- This UK corporation provides transgenic mouse production service and other ancillary services.
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Taconic Animal Models
- Taconic is a commercial supplier of transgenic mice and rats. No custom production offered.
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genOway
- genOway develops transgenic in vivo / in vitro models: DNA microinjections, Knock-out / Knock-in mice, embryonic stem cell differentiation, inducible / conditional systems. Location: France
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GM BioSciences Corporation
- Large scale and custom generation of genetically modified mice for use in target validation and medical/basic research.
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Ozgene
- Commercial venture established to produce genetically modified mice. Location : Australia
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The Mouse Genome Project
- Chromosome 11 genomic database. Includes information about anchoring BACs from RPCI-23 library to the genetic markers, physical map, and end sequences of the BACs. Baylor College of Medicine .
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Mouse Radiation Hybrid Mapping Project
- Features a high-density transcription map of the mouse genome. Includes current status, PCR protocols, bibliography, and related links .
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Mouse Phenome Database
- Collaborative collection of baseline phenotypic data on inbred mouse strains. Includes data sets, protocols, projects and publications, and SNPs.
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RHdb - European Bioinformatics Institute
- Database of raw data used in constructing radiation hybrid maps. This includes STS data, scores, experimental conditions, and cross references.
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The Mouse Genome
- Genetic and physical genome maps . Includes a human and mouse synteny table. Data and image maps can be downloaded .
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U.S. Pig Gene Mapping
- Coordination programe for swine gene mapping. Features a range of detail including linkage and physical maps, databases, activities, and education.
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Cytogenetic Map of the Pig
- Features drawings of genes and markers mapped on chromosome, and a listing of mapped genes and genetic markers .
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PiGBASE
- Searchable genome database of Sus Scrofa . Includes loci, genes, markers, clones, and libraries.
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Swine Genetics Handbook
- Topics range from economic impact of genetic improvement through inbreeding, multiple trait selection and crossbreeding systems.
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Pig Expressed Sequence Tags
- Searchable database of pig reproduction ESTs . Includes summary tables and related resources.
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Cattle Genome Mapping Project
- Includes chromosome maps, marker information for markers used in the genomic and locus scans, and marker searching by name .
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Bovmap Database
- Genome mapping project at L'Institut National de la Recherche Agronomique . Includes loci, gene, and phenes lists, and chromosome homology.
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The Dog Genome Project
- A collaborative study aimed at producing a map of all the chromosomes . Includes a codon frequency table and how the genes are mapped.
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